Title
Monte Carlo Simulation for the Investigation of the Transport of Ions through a Gramicidin Ion Channel
Authors
Keka Talukdar
Department of Physics, Nadiha High School, Durgapur-713211, West Bengal, India.
*Corresponding author E-mail address: keka.talukdar@yahoo.co.in
Article History
Publication details: Received: 06th May 2021; Revised: 28th June 2021; Accepted: 28th June 2021; Published: 24th July 2021
Cite this article
Keka Talukdar. Monte Carlo Simulation for the Investigation of the Transport of Ions through a Gramicidin Ion Channel. Nano Prog., 2021, 3(6), 7-10.
Abstract
Ion channels are the pores through the protein or membrane through which ions can pass. These pores are opened and closed depending on various factors such as change of voltage or binding with ligands. These changes bring some conformational changes to the channel and some selective ions are allowed to pass through the pores. Ion channels are found everywhere in our body, like the nervous system, sperm tail, muscle, etc. Gramicidin is a model membrane protein which when bound with lipid, tells about the protein-lipid interaction and it is suitable for analyzing the structure-function relationship of an ion channel. Here a voltage-gated and lipid-bound gramicidin ion channel is simulated by the Monte Carlo method for a mammalian cell and a squid axon to find the number of ion crossing in both directions across a cell.
Keywords
Ion channel; Monte Carlo simulation; ion transport; voltage gated channel
